New research found that oncogene SET/TAF1, which was found to be a proto-oncogene of acute myeloid leukemia (AML), contributes to proper chromosome partitioning as a tension sensor. Additionally, ...

Cells constantly experience and generate mechanical forces that govern processes from embryonic development to tissue repair and disease progression. Mechanical tension sensing refers to the ...

For the first time, researchers quantify the mechanical forces cells exert on one another. A series of rodent experiments showed that even with abundant food and water, personal space is essential to ...

A Waseda University-led research uncovered the molecular mechanism of how a particular cancer-causing oncogene could trigger an onset of acute myeloid leukemia (AML). Characterized by symptoms such as ...