ascopubs.org

Pharmacokinetic–pharmacodynamic (PK-PD) modeling and simulation of serdemetan-induced QTc effects in a first-in-human study.

Bioavailability of the hedgehog pathway inhibitor GDC-0449 in a phase I pharmacokinetic (PK) study in healthy female subjects. Background: Serdemetan is a compound that can cause replicative stress ...
ascopubs.org

Pharmacokinetic modeling and simulation (PK M&S) supported dose escalation of PF-03446962, a monoclonal antibody (mAb) against activin receptor like kinase 1, in patients with ...

Modeling the combined efficacy of rilotumumab (R; AMG 102) plus epirubicin/cisplatin/capecitabine (ECX) for the treatment of locally advanced or metastatic gastric or ...
Nasdaq

Endo Reports Findings From PK Simulation Modeling Study In Men With Hypogonadism

(RTTNews) - Endo International plc (ENDP) published data from a population pharmacokinetic modeling and simulation study, evaluating potential dosing flexibility of AVEED (testosterone undecanoate) in ...
Business Wire

Certara Launches Version 8.2 of Its Industry-Leading Phoenix PK/PD Modeling and Simulation Software for Drug Development

PRINCETON, NJ--(BUSINESS WIRE)--Certara®, the global model-informed drug development and decision support leader, today announced the launch of Phoenix® 8.2, the ...
Business Wire

Certara Launches Version 8.1 of its Industry-leading Phoenix PK/PD Modeling and Simulation Software; Introduces Professional Certification Program

PRINCETON, N.J.--(BUSINESS WIRE)--Certara®, the global leader in model-informed drug development, regulatory science, market access and real-world evidence services, today announced the launch of ...