A recent study, led by Professor Wu (Wenzhou Institute University, Wenzhou Medical University) and Professor Huang (Northeastern University), explores liquid–liquid phase separation (LLPS), a ...

The interior of a cell is packed with proteins and nucleic acids, such as RNA, all of which need to perform specific functions at the exact right time. If they don’t, serious diseases—ALS, ...

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing cellular life, yet why some RNAs cluster more readily than ...

Scientists at St. Jude Children's Research Hospital have reconciled two closely related but contentious mechanisms underlying transcription, the process of converting genetic information in DNA into ...

Ion-pairing reversed-phase liquid chromatography (IP-RPLC), a standard method to characterize small oligonucleotides, can also separate large RNA molecules. Its advantages extend beyond simple ...

LLPS as a rising molecular entity in the cytoplasm regulates diseases progression via a variety of ways. For example, the relationship between LLPS and cancer can be summarized into six aspects: gene ...