Proteins are the molecular workhorses of the human body. They perform a vast range of essential functions, from building ...

Researchers capture first-of-its-kind video of dynein–Lis1 protein interaction, supporting future drug development for neurological disorders. Our cells rely on microscopic highways and specialized ...

Scientists have used deep learning to design new proteins that bind to complexes involving other small molecules like hormones or drugs, opening up a world of possibilities in the computational design ...

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

Among proteins, the G-protein-coupled receptors (GPCRs), are central to how cells sense and respond to external stimuli. To carry out their signaling, GPCRs rely on a delicate interplay between ...

During an infection, viruses interact with the host’s proteome, initiating processes that lead to viral genome replication, encapsidation, and the release of new progeny. These processes are ...

Liquid-liquid phase transitions govern a wide range of protein-protein and protein-RNA interactions. Although the importance of multivalency and protein disorder in driving these transitions is clear, ...