DNA-based information is a new interdisciplinary field linking information technology and biotechnology. The field hopes to meet the enormous need for long-term data storage by using DNA as an ...

Though the harnessing of antibiotics is one of the most significant human innovations, their efficacy is continuously eroded by the craftiness of their microbial targets. Once a single bacterium ...

Genetic modules are often designed and implemented with inspiration from engineering disciplines. Although this approach can be successful because of the similarities underpinning physical and ...

The term “plasmid” was coined by Joshua Lederberg in 1952 to describe extrachromosomal genetic elements observed during studies of bacterial conjugation and antibiotic resistance. Their transformation ...

Plasmids are extrachromosomal mobile genetic elements whose copy numbers (PCNs) critically influence microbial evolution, antibiotic resistance and pathogenicity. Despite their importance and immense ...

Adeno-associated virus (AAV) vectors play a pivotal role in gene therapy, delivering therapeutic genes with high precision and safety. However, a significant challenge in the biomanufacturing of these ...

Genes responsible for antimicrobial resistance (AMR) can spread from microbe to microbe through circular genetic material called plasmids, and this lateral transfer occurs in the gut. This week in ...