Quantitative phase microscopy (QPM) has emerged as a revolutionary tool, enabling label-free imaging of biological specimens without the need for disruptive dyes or stains 1. This technique preserves ...

A new laser-enhanced cryo-EM technique boosts signal quality, helping scientists study proteins previously too small or ...

Quantitative phase imaging (QPI) applied to holographic microscopy harnesses coherent light interference to record both intensity and phase information, enabling label-free visualisation of ...

A new microscope method reveals details that were difficult to see before, helping researchers study proteins, cells, and ...

Berkeley Lab and UC Berkeley physicists' new technique offers detailed images of the small molecules and cell structures that ...

Researchers have introduced a solution to the problem of light-sheet fluorescence microscopy: novel illumination beams designed based on deep learning using a trainable phase mask. Their study ...

Installed in a custom Titan Krios, the laser phase plate enhances motion correction, early‑frame recovery, and 3D classification and alignment.

A new kind of microscope is giving scientists a way to watch life inside cells with a clarity that feels almost unfair. Instead of choosing between seeing big structures or tiny particles, researchers ...

AIMED allows microscopes to image multiple depth layers simultaneously, producing detailed 3D reconstructions with reduced ...

(A) When a traditional Gaussian beam is used, diffraction causes the illumination beam to widen at the edges. (B) Joint optimization scheme. A network predicts the positions of beads in the focal ...