ascopubs.org

Microarray Gene Expression Profiling of B-Cell Chronic Lymphocytic Leukemia Subgroups Defined by Genomic Aberrations and VH Mutation Status

One hundred genetically well-characterized B-CLL samples, together with 11 healthy control samples, were analyzed using oligonucleotide arrays, which test for the expression of some 12,000 human genes ...
eLife

Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling

Computational assessment identifies probe binding errors in a widely used commercial platform for spatial transcriptomics.
EurekAlert!

Microarray analysis of differential expression of long non-coding RNAs in peripheral blood mononuclear cells in luminal a breast cancer

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers. This study aimed to ...
ascopubs.org

RNA-Seq based gene expression profiling of baseline and on-treatment breast tumors to predict response to HER2-directed therapy, without chemotherapy (TBCRC026).

Breast Cancer Index re-stratifies 21-gene assay risk groups for late distant recurrence and extended endocrine therapy benefit: Results from the BCI Registry Study. This is an ASCO Meeting Abstract ...
eLife

Single-cell co-mapping reveals relationship between chromatin state and gene expression in early zebrafish development

A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.