If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

DNA replication in differentiated cells follows a defined program, but when and how it is established during mammalian development is not known. Here we show using single-cell sequencing, that late ...

Some microbial lineages have undergone substantial genome reduction over evolutionary time, resulting in naturally evolved cells that reveal fundamental principles of cell biology under reduced ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...