Medical Xpress

Inflammation and metabolic stress combine to drive a new cell death pathway—mitoxyperilysis

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, ...
AlphaGalileo

Paligenosis: dual potential of mature cell plasticity in regeneration and tumorigenesis

Paligenosis defines a tightly controlled program through which terminally differentiated cells re‑enter the cell cycle and ...
EurekAlert!

CNDP2 activates the MAPK pathway and arrests the cell cycle, acting as a functional tumor suppressor in gastric cancer. (IMAGE)

Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted.
Frontiers

Integration of Immune Processes and Cell Death in the Pathogenesis of Human Disorders

The interplay between immune responses and cell death pathways is a central theme in immunology and pathology. Recent developments emphasize that these ...
Technology Networks

Targeting Mitochondrial Pathways To Reverse Cellular Senescence

Metabolic reprogramming and circadian disruption drive cellular senescence. Discover how repurposing vutiglabridin to target ...
ascopubs.org

Amivantamab treatment and intra-tumoral gene expression and immune cell changes in refractory metastatic colorectal cancer (mCRC): Whole transcriptome RNA-sequencing analysis ...

Outcomes of young-onset colorectal cancer vs late-onset colorectal cancer patients on phase 1 matched and non-matched therapies. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.
The Scientist

Introducing a New Version of the Cell Cycle

Inside the human airway, a certain cell type reigns supreme: multiciliated cells, decorated with dozens of hair-like cilia all beating in tandem. These cells are responsible for clearing out foreign ...