Periventricular leukomalacia (PVL), the major substrate of neurologic deficits in premature infants, is associated with reduced white matter volume. Using immunomarkers of axonal pathology [β-amyloid ...
1 Clinical Neurochemistry Laboratory, nstitute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden Objective To ...
Wallerian degeneration is an active program tightly associated with axonal degeneration, required for axonal regeneration and functional recovery after nerve damage. Here we provide a functional ...
A collaborative effort between engineers and biologists at the Hong Kong University of Science and Technology (HKUST) has uncovered a neuroprotective mechanism in spinal cord injury (SCI), shedding ...
A direct blow to the head, neck, or face transmits biomechanical forces to the brain that are most commonly acceleratory, deceleratory, or rotational in nature. 1,4 These forces result in diffuse ...
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Injured axons instruct Schwann cells to build specialized actin spheres to break down and remove axon fragments, thereby starting the regeneration process. Damaged peripheral nerves can regenerate ...
Giant axonal neuropathy is a rare, autosomal recessive, pediatric, polysymptomatic, neurodegenerative disorder caused by biallelic loss-of-function variants in GAN, the gene encoding gigaxonin. We ...
Scientists from the Department of Brain Sciences have discovered that the circadian clock regulates axonal regeneration and repair. These findings pave the way for the use of clock-associated ...